Molecular Formula | C22H26N4O3 |
Molar Mass | 394.47 |
Density | 1.36±0.1 g/cm3(Predicted) |
Boling Point | 616.6±55.0 °C(Predicted) |
Solubility | DMSO: soluble15mg/mL (clear solution) |
Appearance | powder |
Color | white to beige |
pKa | 4.72±0.10(Predicted) |
Storage Condition | 2-8°C |
WGK Germany | 3 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.535 ml | 12.675 ml | 25.35 ml |
5 mM | 0.507 ml | 2.535 ml | 5.07 ml |
10 mM | 0.254 ml | 1.268 ml | 2.535 ml |
5 mM | 0.051 ml | 0.254 ml | 0.507 ml |
Biological activity | T863 (DGAT-3) is an effective and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) The oral active inhibitor can act on the acyl-CoA binding site of DGAT1 and inhibit the formation of triacylglycerol mediated by DGAT1. |